Basic Information

Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6 RA-GEF-2 PDZ-GEF2 PDZGEF2 PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2 PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2 Rap Guanine Nucleotide Exchange Factor (GEF) 6 PDZ Domain-Containing Guanine Nucleotide Exchange Factor I KIA001LB RAGEF2
Location (GRCh37)
5:130759766-130970853 UCSC Genome Browser
Location (GRCh38)
5:131424073-131635160
UCSC Genome Browser Search in Marker Scope
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RAPGEF6_0000700 Exon-Exon chr5:130764595-130769351 chr5:131428902-131433658 1035 nt 0.4763
hsa_RAPGEF6_0000900 Exon-Exon chr5:130766552-130769351 chr5:131430859-131433658 720 nt 0.4694
hsa_RAPGEF6_0001000 Exon-Exon chr5:130766552-130791705 chr5:131430859-131456012 1625 nt 0.4498
hsa_RAPGEF6_0002300 Exon-Exon chr5:130769123-130828478 chr5:131433430-131492785 2486 nt 0.4163
hsa_RAPGEF6_0003100 Exon-Exon chr5:130775274-130797781 chr5:131439581-131462088 1289 nt 0.4119
hsa_RAPGEF6_0003200 Exon-Exon chr5:130775274-130799974 chr5:131439581-131464281 1530 nt 0.4072
hsa_RAPGEF6_0005200 Intron-Intron chr5:130775839-130775921 chr5:131440146-131440228 83 nt 0.5422
hsa_RAPGEF6_0006100 Exon-Exon chr5:130782176-130782396 chr5:131446483-131446703 221 nt 0.4751
hsa_RAPGEF6_0006800 Intron-Exon-Intron chr5:130785716-130867887 chr5:131450023-131532194 250 nt 0.3760
hsa_RAPGEF6_0007400 Exon-Exon chr5:130788747-130791705 chr5:131453054-131456012 336 nt 0.3839
Showing 1 to 10 of 253 entries
Forensic Context

A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].