Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0000800 Exon-Exon chr2:61705898-61711240 chr2:61478763-61484105 765 nt 0.3699
hsa_XPO1_0000400 Exon-Exon chr2:61705898-61727029 chr2:61478763-61499894 2865 nt 0.3696
hsa_XPO1_0000500 Exon-Exon chr2:61705898-61729445 chr2:61478763-61502310 2972 nt 0.3688
hsa_XPO1_0000600 Exon-Exon chr2:61705898-61753656 chr2:61478763-61526521 250 nt 0.2920
hsa_XPO1_0001100 Intron-Exon-Intron chr2:61706510-61711713 chr2:61479375-61484578 2844 nt 0.3942
hsa_XPO1_0001200 Intron-Exon-Intron chr2:61706510-61724456 chr2:61479375-61497321 250 nt 0.4080
hsa_XPO1_0002000 Exon-Exon chr2:61708320-61709674 chr2:61481185-61482539 257 nt 0.3502
hsa_XPO1_0002100 Exon-Exon chr2:61708320-61710226 chr2:61481185-61483091 232 nt 0.3534
hsa_XPO1_0002200 Exon-Exon chr2:61708320-61720188 chr2:61481185-61493053 139 nt 0.3597
hsa_XPO1_0002300 Exon-Exon chr2:61708320-61726048 chr2:61481185-61498913 167 nt 0.3892
Showing 111 to 120 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].