This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Forensic Context
A study in mice demonstrated that the CPT1C mRNA was significantly upregulated with increasing radiation dose in lung tissue 48 hours after whole-body irradiation, identifying it as an indicator of high-dose exposure and a marker of senescence and fibrosis [Aryankalayil et al. DOI:10.1080/09553002.2023.2214205].