| ID | Sequence | Length | GC content |
|---|---|---|---|
| AUUGCGUAGUUCCGAAUACCCUCGGCCACACCUGGCCUUCUCCAUGCUC… | 923 nt | 0.5504 | |
| AUUGCGUAGUUCCGAAUACCCUCGGCCACACCUGGCCUUCUCCAUGCUC… | 908 nt | 0.5496 | |
| AUUGCGUAGUUCCGAAUACCCUCGGCCACACCUGGCCUUCUCCAUGCUC… | 924 nt | 0.5487 | |
| AUUGCGUAGUUCCGAAUACCCUCGGCCACACCUGGCCUUCUCCAUGCUC… | 460 nt | 0.5435 | |
| AUUGCGUAGUUCCGAAUACCCUCGGCCACACCUGGCCUUCUCCAUGCUC… | 409 nt | 0.5379 | |
| GAGAAGCCCAGGCAGUUGAGGACAGGAGAGAGAAGGCUGCAGACCCAGA… | 1924 nt | 0.5925 |
This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
A study in Wistar-albino rats demonstrated that the DMKN exhibits a time-dependent expression pattern following mild traumatic brain injury, with decreased expression at 1 hour post-trauma and a gradual increase thereafter [Colak et al. DOI:10.1016/j.injury.2012.01.021].