Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0002700 Exon-Exon chr2:61709515-61715906 chr2:61482380-61488771 950 nt 0.3716
hsa_XPO1_0002800 Exon-Exon chr2:61709515-61717911 chr2:61482380-61490776 1085 nt 0.3742
hsa_XPO1_0002900 Exon-Exon chr2:61709515-61720188 chr2:61482380-61493053 1727 nt 0.3700
hsa_XPO1_0003000 Exon-Exon chr2:61709515-61726048 chr2:61482380-61498913 2382 nt 0.3690
hsa_XPO1_0003100 Exon-Exon chr2:61709515-61727029 chr2:61482380-61499894 2564 nt 0.3686
hsa_XPO1_0003200 Exon-Exon chr2:61709515-61729445 chr2:61482380-61502310 2671 nt 0.3677
hsa_XPO1_0003300 Exon-Exon chr2:61709515-61753656 chr2:61482380-61526521 2846 nt 0.3679
hsa_XPO1_0003400 Exon-Exon chr2:61709515-61761038 chr2:61482380-61533903 2978 nt 0.3697
hsa_XPO1_0004000 Exon-Exon chr2:61710092-61715906 chr2:61482957-61488771 790 nt 0.3759
hsa_XPO1_0004100 Exon-Exon chr2:61710092-61717911 chr2:61482957-61490776 925 nt 0.3784
Showing 11 to 20 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].