Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0004200 Exon-Exon chr2:61710092-61719333 chr2:61482957-61492198 1089 nt 0.3802
hsa_XPO1_0004300 Exon-Exon chr2:61710092-61720188 chr2:61482957-61493053 1567 nt 0.3720
hsa_XPO1_0004400 Exon-Exon chr2:61710092-61726048 chr2:61482957-61498913 2222 nt 0.3704
hsa_XPO1_0004500 Exon-Exon chr2:61710092-61727029 chr2:61482957-61499894 2404 nt 0.3698
hsa_XPO1_0004600 Exon-Exon chr2:61710092-61729445 chr2:61482957-61502310 2511 nt 0.3688
hsa_XPO1_0004700 Exon-Exon chr2:61710092-61753656 chr2:61482957-61526521 2686 nt 0.3690
hsa_XPO1_0004800 Exon-Exon chr2:61710092-61761038 chr2:61482957-61533903 2818 nt 0.3708
hsa_XPO1_0005800 Exon-Exon chr2:61711072-61717911 chr2:61483937-61490776 790 nt 0.3823
hsa_XPO1_0005900 Exon-Exon chr2:61711072-61726048 chr2:61483937-61498913 2087 nt 0.3713
hsa_XPO1_0006600 Exon-Exon chr2:61712903-61715906 chr2:61485768-61488771 486 nt 0.3786
Showing 21 to 30 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].